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CEA antibody [B464M]

Cat. No. GTX44154

Host

Mouse

Clonality

Monoclonal

Clone Name

B464M

Isotype

IgG1

Application

ELISA, IHC, Sandwich ELISA

Reactivity

Human
Package
500 μg ($399)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
ELISA Assay dependent
IHC Assay dependent
Sandwich ELISA Assay dependent

Note :

Sandwich ELISA
Capture : GTX44154, Detection : GTX44158

Not tested in other applications.

Product Note

Does not crossreact with human leukocytes in cytofluorometry.Staining in immunohistochemistry:Brightness 80 Cytoplasmic Staining 3+ Membrane Staining 2+ Background 2+ Staining of Mucus 2+

PROPERTIES

Form

Liquid

Buffer

10mM Tris pH7.5, 0.15M Sodium Chloride

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

5.10 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human natural tumor-derived purified CEA antigen.

Purification

Purified by Ion Exchange Chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

BGP Antibody , BGPI Antibody , BGP1 Antibody , CEACAM1 Antibody

Background

This gene encodes a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregnancy-specific glycoproteins, are located within a 1.2 Mb cluster on the long arm of chromosome 19. Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in the cluster. The encoded protein was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities have been attributed to the encoded protein, including roles in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses. Multiple transcript variants encoding different isoforms have been reported, but the full-length nature of all variants has not been defined. [provided by RefSeq, May 2010]

Research Area

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 399