APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
3-12 μg/mL |
Assay dependent |
Not tested in other applications.
Calculated MW
Product Note
The mouse monoclonal antibody B6.2 recognizes a conformationally dependent epitope of native CD66c, a GPI-anchored extracellular glycoprotein expressed on granulocytes and epithelial cells.
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
15 mM sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Extracts from human breast carcinoma cells
Purification
Protein A purified
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
carcinoembryonic antigen related cell adhesion molecule 6 , CD66c , CEAL , NCA
Cellular Localization
Apical cell membrane , Cell surface
Background
This gene encodes a protein that belongs to the carcinoembryonic antigen (CEA) family whose members are glycosyl phosphatidyl inositol (GPI) anchored cell surface glycoproteins. Members of this family play a role in cell adhesion and are widely used as tumor markers in serum immunoassay determinations of carcinoma. This gene affects the sensitivity of tumor cells to adenovirus infection. The protein encoded by this gene acts as a receptor for adherent-invasive E. coli adhesion to the surface of ileal epithelial cells in patients with Crohn's disease. This gene is clustered with genes and pseudogenes of the cell adhesion molecules subgroup of the CEA family on chromosome 19. [provided by RefSeq, Apr 2014]
Database
Research Area
DATA IMAGES
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GTX04601 FACS Image
FACS analysis of human peripheral whole blood cells using GTX04601 CEACAM6 antibody [B6.2]. Dilution : 3 μg/mL
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GTX04601 FACS Image
FACS analysis of human neutrophil granulocytes using GTX04601 CEACAM6 antibody [B6.2]. Red-filled : Primary antibody Black-dashed : Unlabeled cells Dilution : 3 μg/mL
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REFERENCE
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REVIEW
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