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CEP290 antibody

Anti-CEP290 antibody used in Western Blot (WB). GTX87497

Cat. No. GTX87497

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB

Reactivity

 Human
Package
100 μg ($419)
See all CEP290 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500~1:1000
Not tested in other applications.

Calculated MW

290 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 150mM NaCl, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

The antiserum was produced against synthesized peptide derived from human CEP290 (771-820).

Purification

Purified by antigen-affinity chromatography
From serum

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

3H11Ag , BBS14 , CEP290 , CT87 , JBTS5 , LCA10 , MKS4 , NPHP6 , POC3 , SLSN6 , centrosomal protein 290 , rd16 , centrosomal protein 290kDa

Cellular Localization

Cytoplasm,Cytoskeleton,Microtubule organizing center,Centrosome,Cytoplasm,Cytoskeleton,Microtubule organizing center,Centrosome,Centriolar satellite,Nucleus,Cell projection,Cilium,Cytoplasm,Cytoskeleton,Cilium basal body,Cytoplasm,Cytoskeleton,Microtubule organizing center,Centrosome,Centriole,Cytoplasmic vesicle

Background

This gene encodes a protein with 13 putative coiled-coil domains, a region with homology to SMC chromosome segregation ATPases, six KID motifs, three tropomyosin homology domains and an ATP/GTP binding site motif A. The protein is localized to the centrosome and cilia and has sites for N-glycosylation, tyrosine sulfation, phosphorylation, N-myristoylation, and amidation. Mutations in this gene have been associated with Joubert syndrome and nephronophthisis and the presence of antibodies against this protein is associated with several forms of cancer. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-CEP290 antibody used in Western Blot (WB). GTX87497

GTX87497 WB Image

WB analysis of K562 cell lysates using GTX87497 CEP290 antibody. The lane on the right is blocked with the synthesized peptide.

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 419