GeneTex
United States (US)

CEP350 antibody

CEP350-antibody-GTX87833-IHC-1_18121409_583.jpg

Cat No. GTX87833

Host Rabbit
Clonality Polyclonal
Application IHC-P, ELISA
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-P Assay dependent
ELISA Assay dependent
Not tested in other applications.

Calculated MW

350 kDa. ( Note )

Specificity/Sensitivity

CEP350 Antibody detects endogenous levels of total CEP350 protein.
PROPERTIES

Form

Liquid

Buffer

Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 189% glycerol.

Antigen Species

Human

Immunogen

The antiserum was produced against synthesized peptide derived from human CEP35.

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

centrosomal protein 350kDa, FLJ38282, CE350, CAP350, KIAA0480, gm133, centrosomal protein350kDa, FLJ44058, CEP350

Cellular Localization

Associated with mitotic spindles. Nuclear, in discrete foci. Associated with intermediate filaments. Also present in the pericentrosomal area.

Background

Plays an essential role in centriole growth by stabilizing a procentriolar seed composed of at least, SASS6 and CENPJ. Required for anchoring microtubules to the centrosomes and for the integrity of the microtubule network. Recruits PPARA to discrete subcellular compartments and thereby modulates PPARA activity.
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Database

DATA IMAGES
CEP350-antibody-GTX87833-IHC-1_18121409_583.jpg

GTX87833 IHC-P Image

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using CEP350 Antibody. The picture on the right is treated with the synthesized peptide.

Package List Price ($)
$ 339