*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
CEP350 Antibody detects endogenous levels of total CEP350 protein.
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 189% glycerol.
The antiserum was produced against synthesized peptide derived from human CEP35.
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
centrosomal protein 350kDa, FLJ38282, CE350, CAP350, KIAA0480, gm133, centrosomal protein350kDa, FLJ44058, CEP350
Associated with mitotic spindles. Nuclear, in discrete foci. Associated with intermediate filaments. Also present in the pericentrosomal area.
Plays an essential role in centriole growth by stabilizing a procentriolar seed composed of at least, SASS6 and CENPJ. Required for anchoring microtubules to the centrosomes and for the integrity of the microtubule network. Recruits PPARA to discrete subcellular compartments and thereby modulates PPARA activity.