GeneTex
United States (US)

CFTR antibody

GTX31913_1576_IHC-P_20180221_18121410_256.jpg
GTX31913_3060_WB_20180221_18121410_437.jpg
GTX31913_1575_IHC-P_20180221_18121410_573.jpg

Cat No. GTX31913

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P, ELISA
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1 - 2 μg/mL
IHC-P 5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

168 kDa. ( Note )

Positive Control

Human Small Intestine Tissue Lysate(GTX27923) , Human Small Intestine Tissue Slide
PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

CFTR antibody was raised against an 18 amino acid peptide near the carboxy terminus of human CFTR.The immunogen is located within amino acids 1290 - 1340 of CFTR.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Cystic Fibrosis Transmembrane Conductance Regulator,Abc35,Abcc7,Cf,Cftr/Mrp,Mrp7,Tnr-Cftr,Dj760C5.1,Cftr

Background

This gene encodes a member of the ATP-binding cassette (ABC) transporter superfamily. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily that is involved in multi-drug resistance. The encoded protein functions as a chloride channel and controls the regulation of other transport pathways. Mutations in this gene are associated with the autosomal recessive disorders cystic fibrosis and congenital bilateral aplasia of the vas deferens. Alternatively spliced transcript variants have been described, many of which result from mutations in this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES
GTX31913_1576_IHC-P_20180221_18121410_256.jpg

GTX31913 IHC-P Image

IHC-P analysis of human small intestine tissue using GTX31913 CFTR antibody.
Working concentration : 20 μg/ml

GTX31913_3060_WB_20180221_18121410_437.jpg

GTX31913 WB Image

WB analysis of human small intestine tissue lysate using GTX31913 CFTR antibody.
Working concentration : 1 μg/ml

GTX31913_1575_IHC-P_20180221_18121410_573.jpg

GTX31913 IHC-P Image

IHC-P analysis of human small intestine tissue using GTX31913 CFTR antibody.
Working concentration : 5 μg/ml

Package List Price ($)
$ 329