APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1 - 2 μg/mL |
| 5 μg/mL |
| Assay dependent |
Not tested in other applications.
Calculated MW
Positive Control
Human Small Intestine Tissue Lysate(GTX27923) , Human Small Intestine Tissue Slide
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
CFTR antibody was raised against an 18 amino acid peptide near the carboxy terminus of human CFTR.The immunogen is located within amino acids 1290 - 1340 of CFTR.
Purification
Purified by antigen-affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
cystic fibrosis transmembrane conductance regulator , ABC35 , ABCC7 , CF , CFTR/MRP , MRP7 , TNR-CFTR , dJ760C5.1
Cellular Localization
Apical cell membrane,Cell membrane,Endoplasmic reticulum membrane,Nucleus
Background
This gene encodes a member of the ATP-binding cassette (ABC) transporter superfamily. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily that is involved in multi-drug resistance. The encoded protein functions as a chloride channel and controls the regulation of other transport pathways. Mutations in this gene are associated with the autosomal recessive disorders cystic fibrosis and congenital bilateral aplasia of the vas deferens. Alternatively spliced transcript variants have been described, many of which result from mutations in this gene. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX31913 IHC-P Image
IHC-P analysis of human small intestine tissue using GTX31913 CFTR antibody.
Working concentration : 20 μg/ml
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GTX31913 WB Image
WB analysis of human small intestine tissue lysate using GTX31913 CFTR antibody.
Working concentration : 1 μg/ml
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GTX31913 IHC-P Image
IHC-P analysis of human small intestine tissue using GTX31913 CFTR antibody.
Working concentration : 5 μg/ml
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REFERENCE
There are currently no references for CFTR antibody (GTX31913). Be the first to share your publications with this product.
REVIEW
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