GeneTex
United States (US)

CHD3 antibody [7F6-G2-E5]

GTX16490_ICCIF_18121410_143.jpg
GTX16490_IP_18121410_940.jpg
GTX16490_WB_18121410_655.jpg

Cat No. GTX16490

Host Mouse
Clonality Monoclonal
Clone Name 7F6-G2-E5
Isotype IgG1
Application WB, ICC/IF, IP, ID
Reactivity Human, Mouse, Rat
APPLICATION

Calculated MW

227 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

ascites

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Purified recombinant human CHD3 (C-terminus) protein fragments expressed in E.coli.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Chromodomain Helicase Dna Binding Protein 3,Mi-2A,Mi2-Alpha,Zfh,Chd3

Background

This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES
GTX16490_ICCIF_18121410_143.jpg

GTX16490 ICC/IF Image

ICC/IF analysis of HeLa cells using CHD3 antibody [7F6-G2-E5] at a dilution of 1:400.

GTX16490_IP_18121410_940.jpg

GTX16490 IP Image

IP analysis with HeLa lysates and either control IgG or CHD3 antibody [7F6-G2-E5]. The precipitates were detected by the same antibody.

GTX16490_WB_18121410_655.jpg

GTX16490 WB Image

WB analysis of various cell lysates using CHD3 antibody [7F6-G2-E5] at a dilution of 1:1000.

Package List Price ($)
$ 319