CHI3L1 antibody [HL2708]

Cat. No. GTX639462

Host	Rabbit
Clonality	Monoclonal
Clone Name	HL2708
Isotype	IgG
Application	WB, ICC/IF, IHC-P
Reactivity	Human
Package	100 μl ($399), 25 μl ($169)

See all CHI3L1 products

Datasheet

View product citations for antibody GTX639462 on CiteAb

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Recommended Dilution
WB	1:500-1:3000
ICC/IF	Assay dependent
IHC-P	Assay dependent

Not tested in other applications.

Calculated MW

43 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fragment of human CHI3L1.

Purification

Affinity purified by Protein A.

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

chitinase 3 like 1 , ASRT7 , CGP-39 , GP-39 , GP39 , HC-gp39 , HCGP-3P , YK-40 , YKL-40 , YKL40 , YYL-40 , hCGP-39

Cellular Localization

Cytoplasm,Cytoplasm, perinuclear region,Endoplasmic reticulum

Background

Chitinases catalyze the hydrolysis of chitin, which is an abundant glycopolymer found in insect exoskeletons and fungal cell walls. The glycoside hydrolase 18 family of chitinases includes eight human family members. This gene encodes a glycoprotein member of the glycosyl hydrolase 18 family. The protein lacks chitinase activity and is secreted by activated macrophages, chondrocytes, neutrophils and synovial cells. The protein is thought to play a role in the process of inflammation and tissue remodeling. [provided by RefSeq, Sep 2009]

Database

Gene ID: 1116 CHI3L1
UniProt: P36222 CHI3L1

Research Area

DATA IMAGES

GTX639462 ICC/IF Image

CHI3L1 antibody [HL2708] detects CHI3L1 protein by immunofluorescent analysis.
Sample: THP-1 cells were fixed in 4% paraformaldehyde at RT for 15 min.
Green: CHI3L1 stained by CHI3L1 antibody [HL2708] (GTX639462) diluted at 1:500.
Blue: Fluoroshield with DAPI (GTX30920).

GTX639462 IHC-P Image

CHI3L1 antibody [HL2708] detects CHI3L1 protein at cytoplasm by immunohistochemical analysis.
Sample: Paraffin-embedded human esophageal carcinoma.
CHI3L1 stained by CHI3L1 antibody [HL2708] (GTX639462) diluted at 1:100.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

GTX639462 WB Image

Various whole cell extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with CHI3L1 antibody (GTX639462) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody. Corresponding RNA expression data for the same cell lines are based on Human Protein Atlas program.

REFERENCE

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REVIEW

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Package

List Price ($)

100 μl

$ 399

25 μl

$ 169

Qty Custom Conjugations