GeneTex
United States (US)

CHIT1 antibody

GTX32519_20180530_WB_18121410_362.jpg
GTX32519_20180530_IHC-P_18121410_763.jpg

Cat No. GTX32519

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P
Reactivity Human, Mouse
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

52 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 217-466 of human CHIT1 (NP_003456.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Chitinase 1,Chi3,Chit,Chitd,Chit1

Background

Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. Several alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jan 2012]

Database

Research Area

DATA IMAGES
GTX32519_20180530_WB_18121410_362.jpg

GTX32519 WB Image

WB analysis of various samples using GTX32519 CHIT1 antibody.
Dilution : 1:1000
Loading : 25μg per lane

GTX32519_20180530_IHC-P_18121410_763.jpg

GTX32519 IHC-P Image

IHC-P analysis of human stomach tissue using GTX32519 CHIT1 antibody.
Dilution : 1:200

Package List Price ($)
$ 329