GeneTex
United States (US)

CHMP1B antibody

GTX32520_20180530_IHC-P_18121410_377.jpg
GTX32520_20180530_IHC-P_2_18121410_403.jpg
GTX32520_20180530_WB_18121410_104.jpg
GTX32520_20180530_IHC-P_1_18121410_674.jpg

Cat No. GTX32520

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:100
Not tested in other applications.

Calculated MW

22 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-199 of human CHMP1B (NP_065145.2).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Charged Multivesicular Body Protein 1B,C10Orf2,C18-Orf2,C18Orf2,Chmp1.5,Vps46-2,Vps46B,Hvps46-2,Chmp1B

Background

CHMP1B belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).[supplied by OMIM, Mar 2008]

Database

Research Area

DATA IMAGES
GTX32520_20180530_IHC-P_18121410_377.jpg

GTX32520 IHC-P Image

IHC-P analysis of human liver injury tissue using GTX32520 CHMP1B antibody.
Dilution : 1:100

GTX32520_20180530_IHC-P_2_18121410_403.jpg

GTX32520 IHC-P Image

IHC-P analysis of rat brain tissue using GTX32520 CHMP1B antibody.
Dilution : 1:100

GTX32520_20180530_WB_18121410_104.jpg

GTX32520 WB Image

WB analysis of various samples using GTX32520 CHMP1B antibody.
Dilution : 1:1000
Loading : 25μg per lane

GTX32520_20180530_IHC-P_1_18121410_674.jpg

GTX32520 IHC-P Image

IHC-P analysis of mouse kidney tissue using GTX32520 CHMP1B antibody.
Dilution : 1:100

Package List Price ($)
$ 329