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CHMP1B antibody

Anti-CHMP1B antibody used in Western Blot (WB). GTX32520
Anti-CHMP1B antibody used in IHC (Paraffin sections) (IHC-P). GTX32520
Anti-CHMP1B antibody used in IHC (Paraffin sections) (IHC-P). GTX32520
Anti-CHMP1B antibody used in IHC (Paraffin sections) (IHC-P). GTX32520

Cat. No. GTX32520

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all CHMP1B products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:100
Not tested in other applications.

Calculated MW

22 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-199 of human CHMP1B (NP_065145.2).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

charged multivesicular body protein 1B , C10orf2 , C18-ORF2 , C18orf2 , CHMP1.5 , Vps46-2 , Vps46B , hVps46-2

Cellular Localization

Cytoplasm, cytosol,Endosome

Background

CHMP1B belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).[supplied by OMIM, Mar 2008]

Database

Research Area

DATA IMAGES

Anti-CHMP1B antibody used in Western Blot (WB). GTX32520

GTX32520 WB Image

WB analysis of various sample lysates using GTX32520 CHMP1B antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-CHMP1B antibody used in IHC (Paraffin sections) (IHC-P). GTX32520

GTX32520 IHC-P Image

IHC-P analysis of human liver damage tissue using GTX32520 CHMP1B antibody.
Dilution : 1:100

Anti-CHMP1B antibody used in IHC (Paraffin sections) (IHC-P). GTX32520

GTX32520 IHC-P Image

IHC-P analysis of mouse kidney tissue using GTX32520 CHMP1B antibody.
Dilution : 1:100

Anti-CHMP1B antibody used in IHC (Paraffin sections) (IHC-P). GTX32520

GTX32520 IHC-P Image

IHC-P analysis of rat brain tissue using GTX32520 CHMP1B antibody.
Dilution : 1:100

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399