GeneTex
United States (US)

CIDE A peptide

Cat No. GTX28434

Application Blocking
Species Mouse
APPLICATION

Application Note

The peptide is used for blocking the activity of mCIDE-A (GTX28402). Incubating the peptide with equal volume of antibody for 30 min at 37ºC usually completely blocksthe antibody activity in Western blotting.
PROPERTIES

Form

Liquid

Buffer

PBS pH7.2 with 10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl, 0.1% bovine serum albumin, and 0.02% sodium azide

Storage

Store the peptide at -20˚C, stable for one year.

Concentration

0.20 mg/ml (Please refer to the vial label for the specific concentration.)

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Cell Death-Inducing Dna Fragmentation Factor, Alpha Subunit-Like Effector A,Aw212747,Cidea

Background

This gene encodes the homolog of the mouse protein Cidea that has been shown to activate apoptosis. This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice that lack functional Cidea have higher metabolic rates, higher lipolysis in brown adipose tissue and higher core body temperatures when subjected to cold. These mice are also resistant to diet-induced obesity and diabetes. This suggests that in mice this gene product plays a role in thermogenesis and lipolysis.

Research Area

Package List Price ($)
$ 179