*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
HeLa , PC-12 , Rat2
Mouse, Bovine, Pig, Rhesus Monkey(>80% identity)
1XPBS, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
1mg/ml(Please refer to the vial label for the specific concentration.)
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human CIS. The exact sequence is proprietary.
Purified by antigen-affinity chromatography.
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
CIS antibody, CIS-1 antibody, G18 antibody, SOCS antibody, CISH antibody, suppressor of cytokine signaling antibody, cytokine-inducible inhibitor of signaling type 1B antibody, cytokine-inducible SH2-containing protein antibody, cytokine inducible SH2-containing protein antibody
The protein encoded by this gene contains a SH2 domain and a SOCS box domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by IL2, IL3, GM-CSF and EPO in hematopoietic cells. Proteasome-mediated degradation of this protein has been shown to be involved in the inactivation of the erythropoietin receptor. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
GTX100216 WB Image
CIS antibody [C2C3], C-term detects CISH protein by Western blot analysis.
A. 30 µg PC-12 whole cell lysate/extract
B. 30 µg Rat2 whole cell lysate/extract
12 % SDS-PAGE
CIS antibody [C2C3], C-term (GTX100216) dilution: 1:1000
GTX100216 IHC-P Image
Immunohistochemical analysis of paraffin-embedded human lung cancer, using CIS(GTX100216) antibody at 1:100 dilution.
Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min
GTX100216 ICC/IF Image
Immunofluorescence analysis of paraformaldehyde-fixed A431, using CIS(GTX100216) antibody at 1:200 dilution.
GTX100216 WB Image
Sample (1 ug of whole cell lysate)
10% SDS PAGE
GTX100216 diluted at 1:10000