GeneTex

  • Country / Location Selection

United States (US)

CLCNKB antibody, N-term

Anti-CLCNKB antibody, N-term used in Western Blot (WB). GTX47709

Cat. No. GTX47709

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC

Reactivity

 Human, Mouse
Package
50 μg ($399)
See all CLCNKB products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 0.2-2.5 ug/ml
IHC Assay dependent
Not tested in other applications.

Calculated MW

75 kDa. ( Note )

Positive Control

Jurkat

PROPERTIES

Form

Liquid

Buffer

PBS, 2% Sucrose

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5-1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthetic peptide corresponding to a N-terminal region of Human CLCNKB

Purification

Affinity Purified

Conjugation

Unconjugated

RRID

AB_11177926

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

chloride voltage-gated channel Kb , CLCKB , ClC-K2 , ClC-Kb

Cellular Localization

Cell membrane; Multi-pass membrane protein

Background

The protein encoded by this gene is a member of the family of voltage-gated chloride channels. Chloride channels have several functions, including the regulation of cell volume, membrane potential stabilization, signal transduction and transepithelial transport. This gene is expressed predominantly in the kidney and may be important for renal salt reabsorption. Mutations in this gene are associated with autosomal recessive Bartter syndrome type 3 (BS3). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

Database

Research Area

DATA IMAGES

Anti-CLCNKB antibody, N-term used in Western Blot (WB). GTX47709

GTX47709 WB Image

WB analysis of Jurkat cells using GTX47709 CLCNKB antibody at 0.2-1μg/ml.
Lane A : Marker
Lane B : Jurkat cells

REFERENCE

Application Reference

Liu Z et al. Development 2015; 142 (6) : 1193-202 Second-generation Notch1 activity-trap mouse line (N1IP::CreHI) provides a more comprehensive map of cells experiencing Notch1 activity.
Application : IHC
Reactivity : Mouse
Submit a Reference

REVIEW

There are currently no reviews for CLCNKB antibody, N-term (GTX47709). Be the first to share your experience with this product.
Submit a Review
SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399