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CLN6 antibody

Anti-CLN6 antibody used in IHC (Paraffin sections) (IHC-P). GTX03465
Anti-CLN6 antibody used in Western Blot (WB). GTX03465

Cat. No. GTX03465

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Rat
Package
100 μl ($399)
See all CLN6 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:1000
IHC-P 1:50-1:200
Not tested in other applications.

Calculated MW

36 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS pH7.2, 50% glycerol

Preservative

0.02% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide, corresponding to amino acids 229-274 of Human CLN6.

Purification

Purified by antigen-affinity chromatography
From serum

Purity

>95% by SDS-PAGE

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CLN6 transmembrane ER protein , CLN4A , HsT18960 , nclf

Cellular Localization

Endoplasmic reticulum membrane , Endoplasmic reticulum

Background

This gene is one of eight which have been associated with neuronal ceroid lipofuscinoses (NCL). Also referred to as Batten disease, NCL comprises a class of autosomal recessive, neurodegenerative disorders affecting children. The genes responsible likely encode proteins involved in the degradation of post-translationally modified proteins in lysosomes. The primary defect in NCL disorders is thought to be associated with lysosomal storage function. [provided by RefSeq, Oct 2008]

Database

Research Area

DATA IMAGES

Anti-CLN6 antibody used in IHC (Paraffin sections) (IHC-P). GTX03465

GTX03465 IHC-P Image

IHC-P analysis of human stomach carcinoma tissue using GTX03465 CLN6 antibody.
Left : Primary antibody
Right : Negative control; PBS instead of primary antibody.
Dilution : 1:50

Anti-CLN6 antibody used in Western Blot (WB). GTX03465

GTX03465 WB Image

WB analysis of various sample lysates using GTX03465 CLN6 antibody.
Lane1 : SGC7901 whole cell lysate
Lane 2 : SK-OVCAR3 whole cell lysate
Lane3 : MCF-7 whole cell lysate
Lane4 : PC12 whole cell lysate
Lane5 : CT26 whole cell lysate
Dilution : 1:500
Loading : 40μg per lane

REFERENCE

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REVIEW

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Package List Price ($)
$ 399