GeneTex
United States (US)

CLOCK antibody

Cat No. GTX30118

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ChIP assay
Reactivity Human, Mouse
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:1000
ChIP assay 1:10 - 1:500
Not tested in other applications.

Calculated MW

96 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

Serum, 0.05% Sodium Azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent(Please refer to the vial label for the specific concentration.)

Antigen Species

Mouse

Immunogen

Two peptides derived from mouse CLOCK conjugated to albumin. [UniProt# O08785]

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

5330400M04Rik antibody , KAT13D antibody

Cellular Localization

Cytoplasm,Nucleus

Background

ARNTL/2-CLOCK heterodimers activate E-box element (3'-CACGTG-5') transcription of a number of proteins of the circadian clock. Activates transcription of PER1 and PER2. This transcription is inhibited in a feedback loop by PER and CRY proteins. Has intrinsic histone acetyltransferase activity and this enzymatic function contributes to chromatin-remodeling events implicated in circadian control of gene expression. Acetylates primarily histones H3 and H4. Acetylates also a non-histone substrate: its own partner, ARNTL.

Database

Research Area

Package List Price ($)
$ 329