GeneTex
United States (US)

CLPS antibody

GTX53973_20180530_WB_18121410_828.jpg
GTX53973_20180530_ICCIF_18121410_442.jpg

Cat No. GTX53973

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF
Reactivity Human, Mouse
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
ICC/IF Assay dependent
Not tested in other applications.

Calculated MW

12 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant funsion protein containing a sequence corresponding to amino acids 18-112 of human CLPS (NP_001823.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Background

The protein encoded by this gene is a cofactor needed by pancreatic lipase for efficient dietary lipid hydrolysis. It binds to the C-terminal, non-catalytic domain of lipase, thereby stabilizing an active conformation and considerably increasing the overall hydrophobic binding site. The gene product allows lipase to anchor noncovalently to the surface of lipid micelles, counteracting the destabilizing influence of intestinal bile salts. This cofactor is only expressed in pancreatic acinar cells, suggesting regulation of expression by tissue-specific elements. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]

Database

Research Area

DATA IMAGES
GTX53973_20180530_WB_18121410_828.jpg

GTX53973 WB Image

WB analysis of mouse pancreas tissue lysate using GTX53973 CLPS antibody.
Dilution : 1:1000
Loading : 25μg per lane

GTX53973_20180530_ICCIF_18121410_442.jpg

GTX53973 ICC/IF Image

ICC/IF analysis of HeLa cell using GTX53973 CLPS antibody.
Blue : DAPI

Package List Price ($)
$ 319