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CNG Channel antibody [CNC 9C1]

Anti-CNG Channel antibody [CNC 9C1] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX79456
Anti-CNG Channel antibody [CNC 9C1] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX79456
Anti-CNG Channel antibody [CNC 9C1] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX79456

Cat. No. GTX79456

Reference 1

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 CNC 9C1

Isotype

 IgG1

Application

 WB, ICC/IF, IHC

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all CNG Channel products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:5000
ICC/IF 1:10-1:100
IHC 1:1000
Not tested in other applications.

Calculated MW

80 kDa. ( Note )

Product Note

This antibody is specific to the a2 subunit of the CNG channel.

PROPERTIES

Form

Liquid

Buffer

Ascites

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

MBP-fusion protein of the C-terminal region of the a2 subunit (amino acids K581-D670)

Purification

Unpurified

Conjugation

Unconjugated

RRID

AB_11167547

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

cyclic nucleotide gated channel alpha 1 , CNCG , CNCG1 , CNG-1 , CNG1 , RCNC1 , RCNCa , RCNCalpha , RP49

Cellular Localization

Membrane; Multi-pass membrane protein

Background

The protein encoded by this gene is involved in phototransduction. Along with another protein, the encoded protein forms a cGMP-gated cation channel in the plasma membrane, allowing depolarization of rod photoreceptors. This represents the last step in the phototransduction pathway. Defects in this gene are a cause of retinitis pigmentosa autosomal recessive (ARRP) disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]

Database

Research Area

DATA IMAGES

Anti-CNG Channel antibody [CNC 9C1] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX79456

GTX79456 ICC/IF Image

ICC/IF analysis of U251 cells using GTX79456 CNG Channel antibody [CNC 9C1]. Cells were probed without (right) or with(left) an antibody.
Green : Primary antibody
Blue : Nuclei
Red : Actin
Fixation : formaldehyde
Dilution : 1:20 overnight at 4ºC

Anti-CNG Channel antibody [CNC 9C1] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX79456

GTX79456 ICC/IF Image

ICC/IF analysis of B-3 cells using GTX79456 CNG Channel antibody [CNC 9C1]. Cells were probed without (right) or with(left) an antibody.
Green : Primary antibody
Blue : Nuclei
Red : Actin
Fixation : formaldehyde
Dilution : 1:20 overnight at 4ºC

Anti-CNG Channel antibody [CNC 9C1] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX79456

GTX79456 ICC/IF Image

ICC/IF analysis of HeLa cells using GTX79456 CNG Channel antibody [CNC 9C1]. Cells were probed without (right) or with(left) an antibody.
Green : Primary antibody
Blue : Nuclei
Red : Actin
Fixation : formaldehyde
Dilution : 1:20 overnight at 4ºC

REFERENCE

Application Reference

Yuki Otsuka et al. iScience 2022; 25 (4) : 103987 One-step induction of photoreceptor-like cells from human iPSCs by delivering transcription factors.
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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 399