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COL18A1 antibody, N-term

Anti-COL18A1 antibody, N-term used in Flow cytometry (FACS). GTX80984
Anti-COL18A1 antibody, N-term used in Western Blot (WB). GTX80984

Cat. No. GTX80984

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, FACS

Reactivity

 Human, Mouse
Package
400 μl ($399)
See all Endostatin products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:1000
FACS 1:10-1:50
Not tested in other applications.

Calculated MW

178 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide between 237-263 amino acids from the N-terminal region of human COL18A1.

Purification

Protein A purified, followed by peptide affinity purification.

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

collagen type XVIII alpha 1 chain , KNO , KNO1 , KS

Cellular Localization

Secreted

Background

This gene encodes the alpha chain of type XVIII collagen. This collagen is one of the multiplexins, extracellular matrix proteins that contain multiple triple-helix domains (collagenous domains) interrupted by non-collagenous domains. A long isoform of the protein has an N-terminal domain that is homologous to the extracellular part of frizzled receptors. Proteolytic processing at several endogenous cleavage sites in the C-terminal domain results in production of endostatin, a potent antiangiogenic protein that is able to inhibit angiogenesis and tumor growth. Mutations in this gene are associated with Knobloch syndrome. The main features of this syndrome involve retinal abnormalities, so type XVIII collagen may play an important role in retinal structure and in neural tube closure. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]

Database

Research Area

DATA IMAGES

Anti-COL18A1 antibody, N-term used in Flow cytometry (FACS). GTX80984

GTX80984 FACS Image

FACS analysis of 293 cells using GTX80984 COL18A1 antibody, N-term.
Green : primary antibody
Blue : negative control

Anti-COL18A1 antibody, N-term used in Western Blot (WB). GTX80984

GTX80984 WB Image

WB analysis of mouse lung tissue lysate (35ug/lane) using GTX80984 COL18A1 antibody, N-term.

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399