GeneTex
United States (US)

COL1A2 antibody

GTX64468_20180530_IHC-P_18121411_535.jpg
GTX64468_20180530_IHC-P_1_18121411_237.jpg
GTX64468_20180530_WB_18121411_203.jpg

Cat No. GTX64468

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P
Reactivity Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

129 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 500-600 of human COL1A2 (NP_000080.2).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

OI4 Antibody

Background

This gene encodes the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in this gene, however, tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen (COL1A1) reflecting the different role of alpha2 chains in matrix integrity. Three transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish, Feb 2008]

Database

DATA IMAGES
GTX64468_20180530_IHC-P_18121411_535.jpg

GTX64468 IHC-P Image

IHC-P analysis of mouse brain tissue using GTX64468 COL1A2 antibody.
Dilution : 1:100

GTX64468_20180530_IHC-P_1_18121411_237.jpg

GTX64468 IHC-P Image

IHC-P analysis of rat brain tissue using GTX64468 COL1A2 antibody.
Dilution : 1:100

GTX64468_20180530_WB_18121411_203.jpg

GTX64468 WB Image

WB analysis of various samples using GTX64468 COL1A2 antibody.
Dilution : 1:1000
Loading : 25μg per lane

Package List Price ($)
$ 319