GeneTex
United States (US)

COQ3 antibody

GTX33110_20180530_WB_18121410_637.jpg
GTX33110_20180530_IHC-P_18121410_149.jpg
GTX33110_20180530_ICCIF_18121410_469.jpg

Cat No. GTX33110

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF, IHC-P
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:200
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

41 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 50-369 of human COQ3 (NP_059117.3).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Coenzyme Q3, Methyltransferase,Dhhbmt,Dhhbmtase,Ug0215E05,Ba9819.1,Coq3

Background

Ubiquinone, also known as coenzyme Q, or Q, is a critical component of the electron transport pathways of both eukaryotes and prokaryotes (Jonassen and Clarke, 2000 [PubMed 10777520]). This lipid consists of a hydrophobic isoprenoid tail and a quinone head group. The tail varies in length depending on the organism, but its purpose is to anchor coenzyme Q to the membrane. The quinone head group is responsible for the activity of coenzyme Q in the respiratory chain. The S. cerevisiae COQ3 gene encodes an O-methyltransferase required for 2 steps in the biosynthetic pathway of coenzyme Q. This enzyme methylates an early coenzyme Q intermediate, 3,4-dihydroxy-5-polyprenylbenzoic acid, as well as the final intermediate in the pathway, converting demethyl-ubiquinone to coenzyme Q. The COQ3 gene product is also capable of methylating the distinct prokaryotic early intermediate 2-hydroxy-6-polyprenyl phenol.[supplied by OMIM, Mar 2008]

Database

Research Area

DATA IMAGES
GTX33110_20180530_WB_18121410_637.jpg

GTX33110 WB Image

WB analysis of various samples using GTX33110 COQ3 antibody.
Dilution : 1:1000
Loading : 25μg per lane

GTX33110_20180530_IHC-P_18121410_149.jpg

GTX33110 IHC-P Image

IHC-P analysis of mouse brain tissue using GTX33110 COQ3 antibody.
Dilution : 1:100

GTX33110_20180530_ICCIF_18121410_469.jpg

GTX33110 ICC/IF Image

ICC/IF analysis of A549 cell using GTX33110 COQ3 antibody.
Blue : DAPI

Package List Price ($)
$ 329