*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
293T , A431 , HepG2 , Molt-4 , Raji
1XPBS, 40% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
1 mg/ml (Please refer to the vial label for the specific concentration.)
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human COX1. The exact sequence is proprietary.
Purified by antigen-affinity chromatography.
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Prostaglandin-Endoperoxide Synthase 1,Cox1,Cox3,Pcox1,Pes-1,Pgg/Hs,Pghs-1,Pghs1,Phs1,Ptghs,Ptgs1
Microsome membrane; Peripheral membrane protein , Endoplasmic reticulum membrane; Peripheral membrane protein
Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes PTGS1, which regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. PTGS1 is thought to be involved in cell-cell signaling and maintaining tissue homeostasis. Alternative splicing of this gene generates two transcript variants. The expression of these two transcripts is differentially regulated by relevant cytokines and growth factors. [provided by RefSeq]
GTX104634 IHC-P Image
Immunohistochemical analysis of paraffin-embedded PC13 xenograft, using PTGS1 (GTX104634) antibody at 1:100 dilution.
Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min
GTX104634 WB Image
Sample(30 μg of whole cell lysate)
10% SDS PAGE
GTX104634 diluted at 1:500