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COX1 antibody

Anti-COX1 antibody used in IHC (Paraffin sections) (IHC-P). GTX33113
Anti-COX1 antibody used in Western Blot (WB). GTX33113
Anti-COX1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX33113

Cat. No. GTX33113

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all COX1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:200
IHC-P 1:100 - 1:200
Not tested in other applications.

Calculated MW

69 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human PTGS1 (NP_001258094.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

prostaglandin-endoperoxide synthase 1 , COX1 , COX3 , PCOX1 , PES-1 , PGG/HS , PGHS-1 , PGHS1 , PHS1 , PTGHS

Background

This is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. Based on its ability to function as both a cyclooxygenase and as a peroxidase, the encoded protein has been identified as a moonlighting protein. The protein may promote cell proliferation during tumor progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

Database

Research Area

DATA IMAGES

Anti-COX1 antibody used in IHC (Paraffin sections) (IHC-P). GTX33113

GTX33113 IHC-P Image

IHC-P analysis of human liver cancer tissue using GTX33113 COX1 antibody.
Dilution : 1:100

Anti-COX1 antibody used in Western Blot (WB). GTX33113

GTX33113 WB Image

WB analysis of various sample lysates using GTX33113 COX1 antibody. The signal was developed with ECL plus-Enhanced.
Dilution : 1:1000
Loading : 25μg per lane

Anti-COX1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX33113

GTX33113 ICC/IF Image

ICC/IF analysis of HeLa cells using GTX33113 COX1 antibody.
Blue : DAPI
Dilution : 1:100

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399