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CPA1 antibody [MSVA-601M] HistoMAX™

HistoMAX
Anti-CPA1 antibody [MSVA-601M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04433
Anti-CPA1 antibody [MSVA-601M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04433
Anti-CPA1 antibody [MSVA-601M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04433

Cat. No. GTX04433

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 MSVA-601M

Isotype

 IgG1

Application

 IHC-P

Reactivity

 Human
Package
500 μl ($899),
100 μl ($299)
See all CPA1 products
PRODUCT

Summary

This antibody was validated on 76 different Normal Tissues by IHC-P.

Go to Normal Tissue GalleryGo to Cancer Tissue Gallery

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:100-1:200

Note :

IHC-P
Manual staining : Heat-induced antigen retrieval for 5 minutes in an autoclave at 121ºC in pH 7.8 Tris-EDTA-based Target Retrieval Solution buffer.

This antibody has been validated by Autostainer including Agilent/Dako - Autostainer Link 48, Bond RX-Lecia, and Roche-Ventana Discovery ULTRA. The detailed steps by Autostainer please refer to the protocol.
Not tested in other applications.

Calculated MW

47 kDa. ( Note )

Positive Control

Pancreas: A strong CPA1 staining of acinar cells should be seen. Adjacent structures can also be stained due to contamination artifacts.

Negative Control

Colon: CPA1 immunostaining should not be seen.

PROPERTIES

Form

Liquid

Buffer

PBS, 0.05% BSA (Please contact us for PBS only format)

Preservative

0.05% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant full-length human CPA1 protein

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

carboxypeptidase A1 , CPA

Cellular Localization

Secreted

Background

This gene encodes a member of the carboxypeptidase A family of zinc metalloproteases. This enzyme is produced in the pancreas and preferentially cleaves C-terminal branched-chain and aromatic amino acids from dietary proteins. This gene and several family members are present in a gene cluster on chromosome 7. Mutations in this gene may be linked to chronic pancreatitis, while elevated protein levels may be associated with pancreatic cancer. [provided by RefSeq, Jan 2015]

Database

DATA IMAGES

Anti-CPA1 antibody [MSVA-601M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04433

GTX04433 IHC-P Image

IHC-P analysis of human pancreas tissue using GTX04433 CPA1 antibody [MSVA-601M] HistoMAX™.
Strong CPA1 staining in pancreatic acinar cells. Because of the high level of expression, adjacent tissues (stroma; excretory ducts) also exhibit some staining due to a contamination effect.

Anti-CPA1 antibody [MSVA-601M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04433

GTX04433 IHC-P Image

IHC-P analysis of human mucosa from descending colon tissue using GTX04433 CPA1 antibody [MSVA-601M] HistoMAX™.
CPA1 negative mucosa of the colon descendens.

Anti-CPA1 antibody [MSVA-601M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04433

GTX04433 IHC-P Image

IHC-P analysis of human pancreas tissue using GTX04433 CPA1 antibody [MSVA-601M] HistoMAX™.
Strong CPA1 immunostaining in acinar cells of the pancreas.

REFERENCE

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REVIEW

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Package List Price ($)
$ 899
$ 299