GeneTex
United States (US)

CPOX antibody [N2C3]

GTX105056_WB_19011506_622.jpg

Cat No. GTX105056

Reference 1
Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB
Reactivity Human
See all CPOX products
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-1:3000
Not tested in other applications.

Calculated MW

50 kDa. ( Note )

Positive Control

HCT116

Predict Reactivity

Mouse, Rat, Bovine, Pig(>80% identity)
PROPERTIES

Form

Liquid

Buffer

0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.42mg/ml(Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the center region of human CPOX. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

CPO antibody, CPX antibody, HCP antibody, CPOX antibody, coprogen oxidase antibody, "coproporphyrinogen-III oxidase, mitochondrial antibody", COX antibody, coproporphyrinogenase antibody, coproporphyrinogen oxidase antibody

Cellular Localization

Mitochondrion intermembrane space

Background

Coproporphyrinogen oxidase (EC 1.3.3.3) is the sixth enzyme of the heme biosynthetic pathway. This soluble protein is localized in the intermembrane space of mitochondria and catalyzes the conversion of 2 propionate groups at positions 2 and 4 of coproporphyrinogen III to 2 vinyl groups of protoporphyrinogen IX.[supplied by OMIM]

Database

Research Area

DATA IMAGES
GTX105056_WB_19011506_622.jpg

GTX105056 WB Image

Sample (30 ug of whole cell lysate)
A: HCT116 10% SDS PAGE
GTX105056 diluted at 1:1000

REFERENCE

Application Reference

Yang DF et al. J Formos Med Assoc. 2014; 113 (2) : 88-93 Methotrexate enhances 5-aminolevulinic acid-mediated photodynamic therapy-induced killing of human SCC4 cells by upregulation of coproporphyrinogen oxidase.
Application : WB
Reactivity : Human
Submit a Reference
SDS
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 319
$ 169