APPLICATION
Product Note
The peptide was used in the production of GTX89237.
PROPERTIES
Form
Lyophilized powder
Buffer
Reconstitute with 200μl distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O.
Preservative
No preservative
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Region/Sequence
C-DPAQTVEQRLKLFK
Note
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET
Synonyms
Carnitine Palmitoyltransferase 1A , Cpt1 , Cpt1-L , L-Cpt1 , Cpt1A
Background
The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Research Area
REFERENCE
There are currently no references for CPT1A blocking peptide (GTX89237-PEP). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for CPT1A blocking peptide (GTX89237-PEP). Be the first to share your experience with this product.