GeneTex
United States (US)

CRB1 antibody

GTX32103_3229_WB_20180221_18121410_352.jpg

Cat No. GTX32103

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ELISA
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1 - 2 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

154 kDa. ( Note )

Positive Control

Human Small Intestine Tissue Lysate(GTX27923)

Specificity/Sensitivity

Alternatively spliced transcript variants have been observed. CRB1 antibody i spredicted to not cross-react with CRB2.
PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Rabbit polyclonal CRB1 antibody was raised against an 18 amino acid peptide near the center of human CRB1.The immunogen is located within amino acids 780 - 830 of CRB1.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Crumbs 1, Cell Polarity Complex Component,Lca8,Rp12,Crb1

Background

This gene encodes a protein which is similar to the Drosophila crumbs protein and localizes to the inner segment of mammalian photoreceptors. In Drosophila crumbs localizes to the stalk of the fly photoreceptor and may be a component of the molecular scaffold that controls proper development of polarity in the eye. Mutations in this gene are associated with a severe form of retinitis pigmentosa, RP12, and with Leber congenital amaurosis. Alternate splicing results in multiple transcript variants, some protein coding and some non-protein coding.[provided by RefSeq, Apr 2012]

Database

DATA IMAGES
GTX32103_3229_WB_20180221_18121410_352.jpg

GTX32103 WB Image

WB analysis of human small intestine tissue lysate using GTX32103 CRB1 antibody.
Working concentration : 1 μg/ml

Package List Price ($)
$ 329