GeneTex
United States (US)

CRBN antibody

GTX31611_2796_WB_20180221_18121410_725.jpg
GTX31611_1270_IHC-P_20180221_18121410_917.jpg
GTX31611_1271_IHC-P_20180221_18121410_892.jpg

Cat No. GTX31611

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF, IHC-P, ELISA
Reactivity Human, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1 - 2 μg/mL
ICC/IF Assay dependent
IHC-P 5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

51 kDa. ( Note )

Positive Control

Human Testis Tissue Lysate(GTX15374)

Specificity/Sensitivity

At least two isoforms of CRBN are known to exist; this antibody will detect both isoforms.
PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

CRBN antibody was raised against a 16 amino acid peptide near the carboxy terminus of human CRBN.The immunogen is located within the last 50 amino acids of CRBN.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Cereblon,Mrt2,Mrt2A,Crbn

Background

This gene encodes a protein related to the Lon protease protein family. In rodents and other mammals this gene product is found in the cytoplasm localized with a calcium channel membrane protein, and is thought to play a role in brain development. Mutations in this gene are associated with autosomal recessive nonsyndromic mental retardation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]

Database

DATA IMAGES
GTX31611_2796_WB_20180221_18121410_725.jpg

GTX31611 WB Image

WB analysis of human testis tissue lysate using GTX31611 CRBN antibody.
Working concentration : (A) 0.5 and (B) 1 μg/ml

GTX31611_1270_IHC-P_20180221_18121410_917.jpg

GTX31611 IHC-P Image

IHC-P analysis of rat testis tissue using GTX31611 CRBN antibody.
Working concentration : 5 μg/ml

GTX31611_1271_IHC-P_20180221_18121410_892.jpg

GTX31611 IHC-P Image

IHC-P analysis of rat testis tissue using GTX31611 CRBN antibody.
Working concentration : 20 μg/ml

Package List Price ($)
$ 339