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CRBN antibody

Anti-CRBN antibody used in Western Blot (WB). GTX31611
Anti-CRBN antibody used in IHC (Paraffin sections) (IHC-P). GTX31611
Anti-CRBN antibody used in IHC (Paraffin sections) (IHC-P). GTX31611

Cat No. GTX31611

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P, ELISA

Reactivity

Human, Mouse, Rat
Package
100 μg ($339)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1 - 2 μg/mL
IHC-P 5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

51 kDa. ( Note )

Positive Control

Human Testis Tissue Lysate(GTX15374)

Specificity/Sensitivity

At least two isoforms of CRBN are known to exist; this antibody will detect both isoforms.

PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

CRBN antibody was raised against a 16 amino acid peptide near the carboxy terminus of human CRBN.The immunogen is located within the last 50 amino acids of CRBN.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

cereblon , MRT2 , MRT2A

Cellular Localization

Cytoplasm,Nucleus,Membrane

Background

This gene encodes a protein related to the Lon protease protein family. In rodents and other mammals this gene product is found in the cytoplasm localized with a calcium channel membrane protein, and is thought to play a role in brain development. Mutations in this gene are associated with autosomal recessive nonsyndromic mental retardation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]

Database

Research Area

DATA IMAGES

Anti-CRBN antibody used in Western Blot (WB). GTX31611

GTX31611 WB Image

WB analysis of human testis tissue lysate using GTX31611 CRBN antibody.
Working concentration : (A) 0.5 and (B) 1 μg/ml

Anti-CRBN antibody used in IHC (Paraffin sections) (IHC-P). GTX31611

GTX31611 IHC-P Image

IHC-P analysis of rat testis tissue using GTX31611 CRBN antibody.
Working concentration : 5 μg/ml

Anti-CRBN antibody used in IHC (Paraffin sections) (IHC-P). GTX31611

GTX31611 IHC-P Image

IHC-P analysis of rat testis tissue using GTX31611 CRBN antibody.
Working concentration : 20 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 339