*Optimal dilutions/concentrations should be determined by the researcher.
|1:500 - 1:1000
|1:5000 - 1:25000
|0.5-1.0 uL per assay
Not tested in other applications.
A partial cross-reactivity is observed against CREM-1 protein.
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 and 0.01% (w/v) Sodium Azide
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
2.56 mg/ml (Please refer to the vial label for the specific concentration.)
CREB-1 (p43) peptide corresponding to a region near the N-terminus of the human protein, conjugated to Keyhole Limpet Hemocyanin (KLH).
This product was prepared from monospecific antiserum by delipidation and immunoadsorption against an E.coli lysate immobilized on agarose beads.
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Camp Responsive Element Binding Protein 1,Creb,Creb-1,Creb1
cyclic AMP responsive element binding protein (CREB) is a ubiquitous transcription factor regulated by changes in cyclic AMP (cAMP) levels. CREB binds as a homodimer to CRE sites (cAMP response elements) and belongs to the basic leucine zipper family of DNA binding proteins. Increases in cAMP levels result in the specific phosphorylation of CREB by protein kinase A. Phosphorylated CREB interacts with the transcriptional co-activator CBP (CREB binding protein or p265). It has recently been demonstrated that CREB phosphorylation correlates with light regulated circadian rhythms.