GeneTex
United States (US)

CREB3L1 antibody [C3], C-term

GTX104818_39708_20160630_WB_19011506_540.jpg
GTX104818_WB_19011506_393.jpg

Cat No. GTX104818

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-1:3000
Not tested in other applications.

Calculated MW

57 kDa. ( Note )

Positive Control

293T , A431 , HeLa , HepG2 , 293T , A431 , H1299 , HeLaS3 , HepG2 , Molt-4 , Raji

Predict Reactivity

Mouse, Rat(>80% identity)
PROPERTIES

Form

Liquid

Buffer

1XPBS, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1mg/ml(Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human CREB3L1. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

OASIS antibody, CREB3L1 antibody, BBF-2 homolog antibody, cyclic AMP-responsive element-binding protein 3-like protein 1 antibody, old astrocyte specifically-induced substance antibody, old astrocyte specifically induced substance antibody, cAMP-responsive element-binding protein 3-like protein 1 antibody, cAMP responsive element binding protein 3-like 1 antibody

Cellular Localization

Endoplasmic reticulum membrane , Processed cyclic AMP-responsive element-binding protein 3-like protein 1: Nucleus

Background

Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE.

Database

DATA IMAGES
GTX104818_39708_20160630_WB_19011506_540.jpg

GTX104818 WB Image

Various whole cell extracts (30 µg) were separated by 10% SDS-PAGE, and the membrane was blotted with CREB3L1 antibody [C3], C-term (GTX104818) diluted at 1:1000.

GTX104818_WB_19011506_393.jpg

GTX104818 WB Image

Sample(30 μg of whole cell lysate)
A:Hep G2(GTX27900)
B:MOLT4 (GTX27912)
12% SDS PAGE
GTX104818 diluted at 1:1500

SDS
PBS.pdf
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 319
$ 169