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CRF-RII antibody

Anti-CRF-RII antibody used in IHC (Paraffin sections) (IHC-P). GTX71405

Cat No. GTX71405

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

IHC-P

Reactivity

Human
Package
25 μg ($339)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-P 13 μg/ml
Not tested in other applications.

Calculated MW

48 kDa. ( Note )

Predict Reactivity

Mouse, Rat, Rabbit, Bovine, Dog, Hamster, Pig, Monkey, Bat, Elephant, Gibbon, Gorilla, Horse, Marmoset, Panda(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS, 0.1% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic 18 amino acid peptide from 1st extracellular domain of human CRHR2.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

corticotropin releasing hormone receptor 2 , CRF2 , CRFR2 , CRFRB , CRHR2 , HMCRF , CRF-RII , Corticotropin Releasing Factor Receptor 2

Cellular Localization

Cell membrane

Background

The protein encoded by this gene belongs to the G-protein coupled receptor 2 family, and the subfamily of corticotropin releasing hormone receptor. This receptor shows high affinity for corticotropin releasing hormone (CRH), and also binds CRH-related peptides such as urocortin. CRH is synthesized in the hypothalamus, and plays an important role in coordinating the endocrine, autonomic, and behavioral responses to stress and immune challenge. Studies in mice suggest that this receptor maybe involved in mediating cardiovascular homeostasis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jan 2011]

Database

Research Area

DATA IMAGES

Anti-CRF-RII antibody used in IHC (Paraffin sections) (IHC-P). GTX71405

GTX71405 IHC-P Image

IHC-P analysis of human brain, choroid plexus tissue using GTX71405 CRF-RII antibody.
Antigen retrieval : Heat-induced antigen retrieval

REFERENCE

There are currently no references for CRF-RII antibody (GTX71405). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for CRF-RII antibody (GTX71405). Be the first to share your experience with this product.
SDS
PBS.pdf
Sodium Azide.pdf