APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1:500 - 1:2000 |
| 1:50 - 1:200 |
Not tested in other applications.
Calculated MW
PROPERTIES
Form
Liquid
Buffer
PBS, 50% Glycerol
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 400-500 of human DPYSL2 (NP_001377.1).
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
dihydropyrimidinase like 2 , CRMP-2 , CRMP2 , DHPRP2 , DRP-2 , DRP2 , N2A3 , ULIP-2 , ULIP2
Cellular Localization
Cytoplasm, cytosol,Cytoplasm, cytoskeleton,Membrane
Background
This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]
Database
Research Area
DATA IMAGES
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GTX35221 IHC-P Image
IHC-P analysis of rat brain tissue using GTX35221 CRMP2 antibody.
Dilution : 1:400
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GTX35221 IHC-P Image
IHC-P analysis of mouse brain tissue using GTX35221 CRMP2 antibody.
Dilution : 1:400
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GTX35221 WB Image
WB analysis of various sample lysates using GTX35221 CRMP2 antibody.
Dilution : 1:1000
Loading : 25μg per lane
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GTX35221 WB Image
WB analysis of normal (control) and knockout (KO) HeLa cell lysate using GTX35221 CRMP2 antibody.
Dilution : 1:3000
Loading : 25μg per lane
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REFERENCE
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REVIEW
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