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CRMP2 (phospho Thr509) antibody

Orthogonal
Anti-CRMP2 (phospho Thr509) antibody used in Western Blot (WB). GTX55355
Anti-CRMP2 (phospho Thr509) antibody used in IHC (Paraffin sections) (IHC-P). GTX55355

Cat. No. GTX55355

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human
Package
100 μl ($399)
See all CRMP2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:1000
IHC-P 1:50-1:100
Not tested in other applications.

Calculated MW

62 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS (without Mg²⁺ and Ca²⁺) pH7.4, 150mM NaCl, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide sequence around phosphorylation site of threonine 509 (S-V-T(p)-P-K) derived from human CRMP2.

Purification

Purified by antigen-affinity chromatography. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

dihydropyrimidinase like 2 , CRMP-2 , CRMP2 , DHPRP2 , DRP-2 , DRP2 , N2A3 , ULIP-2 , ULIP2

Cellular Localization

Cytoplasm, cytosol,Cytoplasm, cytoskeleton,Membrane

Background

This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]

Database

Research Area

DATA IMAGES

Anti-CRMP2 (phospho Thr509) antibody used in Western Blot (WB). GTX55355

GTX55355 WB Image

Orthogonal

WB analysis of extracts from HT-29 cells treated with heat shock using GTX55355 CRMP2 (phospho Thr509) antibody.
Left : Primary antibody
Right : Primary antibody pre-incubated with the antigen specific peptide

Anti-CRMP2 (phospho Thr509) antibody used in IHC (Paraffin sections) (IHC-P). GTX55355

GTX55355 IHC-P Image

IHC-P analysis of human brain tissue using GTX55355 CRMP2 (phospho Thr509) antibody.
Left : Primary antibody
Right : Primary antibody pre-incubated with the antigen specific peptide

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399