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CSK antibody, C-term

Anti-CSK antibody, C-term used in Western Blot (WB). GTX89784
Anti-CSK antibody, C-term used in IHC (Paraffin sections) (IHC-P). GTX89784
Anti-CSK antibody, C-term used in Western Blot (WB). GTX89784

Cat. No. GTX89784

Host

 Goat

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse
Package
100 μg ($399)
See all CSK products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1-3μg/ml
IHC-P 3-6μg/ml

Note :

IHC-P
Human Colon shows staining of a cell layer between the mucosal columns and the muscularis mucosae.
Not tested in other applications.

Calculated MW

51 kDa. ( Note )

Positive Control

The peptide used to generate this antibody is available for purchase (GTX89784-PEP).

Predict Reactivity

Rat, Bovine, Dog(>80% identity)

PROPERTIES

Form

Liquid

Buffer

TBS, 0.5% BSA

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.50 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide with sequence C-EQLEHIKTHELHL, from the C Terminus of the protein sequence according to NP_004374.1.

Purification

Purified by ammonium sulphate precipitation followed by antigen affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

C-terminal Src kinase

Cellular Localization

Cytoplasm , Cell membrane

Background

The protein encoded by this gene is involved in multiple pathways, including the regulation of Src family kinases. It plays an important role in T-cell activation through its association with the protein encoded by the protein tyrosine phosphatase, non-receptor type 22 (PTPN22) gene. This protein also phosphorylates C-terminal tyrosine residues on multiple substrates, including the protein encoded by the SRC proto-oncogene, non-receptor tyrosine kinase gene. Phosphorylation suppresses the kinase activity of the Src family tyrosine kinases. An intronic polymorphism (rs34933034) in this gene has been found to affect B-cell activation and is associated with systemic lupus erythematosus (SLE). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2017]

Database

Research Area

DATA IMAGES

Anti-CSK antibody, C-term used in Western Blot (WB). GTX89784

GTX89784 WB Image

WB analysis of mouse spleen lysate using GTX89784 CSK antibody, C-term.
Dilution : 1μg/ml
Loading : 35μg protein in RIPA buffer

Anti-CSK antibody, C-term used in IHC (Paraffin sections) (IHC-P). GTX89784

GTX89784 IHC-P Image

IHC-P analysis of human colon using GTX89784 CSK antibody, C-term.
Antigen retrieval : citrate buffer pH 6
Dilution : 4μg/ml

Anti-CSK antibody, C-term used in Western Blot (WB). GTX89784

GTX89784 WB Image

WB analysis of Jurkat lysate using GTX89784 CSK antibody, C-term.
Dilution : 0.5μg/ml
Loading : 35μg protein in RIPA buffer

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 399