GeneTex
United States (US)

CSRP3 antibody, Internal

GTX88505_938_IHC-P_18122102_257.jpg
GTX88505_939_IHC-P_18122102_960.jpg
GTX88505_2274_WB_18122102_848.jpg

Cat No. GTX88505

Host Goat
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 0.01-0.03μg/ml
IHC-P 2.5μg/ml
Not tested in other applications.

Calculated MW

21 kDa. ( Note )

Positive Control

The peptide used to generate this antibody is available for purchase (GTX88505-PEP).

Predict Reactivity

Bovine, Dog(>80% identity)
PROPERTIES

Form

Liquid

Buffer

Tris saline pH7.3, 0.02% sodium azide, 0.5% BSA.

Concentration

0.50mg/ml

Antigen Species

Human

Immunogen

Peptide with sequence CGKSLESTNVTDKD, from the internal region of the protein sequence according to NP_003467.1.

Purification

Purified by ammonium sulphate precipitation followed by antigen affinity chromatography

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

CRP3 Antibody , CMH12 Antibody , LMO4 Antibody , CMD1M Antibody , MLP Antibody , CLP Antibody

Cellular Localization

Mainly cytoplasmic (By similarity). In the nucleus it associates with the actin cytoskeleton (Potential). In the Z-disk, found associated with GLRX3.

Background

This gene encodes a member of the CSRP family of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. The LIM/double zinc-finger motif found in this protein is found in a group of proteins with critical functions in gene regulation, cell growth, and somatic differentiation. Mutations in this gene are thought to cause heritable forms of hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM) in humans. Alternatively spliced transcript variants with different 5' UTR, but encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008]
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Database

DATA IMAGES
GTX88505_938_IHC-P_18122102_257.jpg

GTX88505 IHC-P Image

IHC-P analysis of human heart using GTX88505 CSRP3 antibody, Internal.
Antigen retrieval : citrate buffer pH 6
Dilution : 2.5µg/ml

GTX88505_939_IHC-P_18122102_960.jpg

GTX88505 IHC-P Image

IHC-P analysis of human skeletal muscle using GTX88505 CSRP3 antibody, Internal.
Antigen retrieval : citrate buffer pH 6
Dilution : 2.5µg/ml

GTX88505_2274_WB_18122102_848.jpg

GTX88505 WB Image

WB analysis of human (A), mouse (B) and rat (C) heart lysate using GTX88505 CSRP3 antibody, Internal.
Dilution : 0.01µg/ml
Loading : 35µg protein in RIPA buffer

Reference
Package List Price ($)
$ 329