APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Dilution |
1:500-1:3000 |
Not tested in other applications.
Calculated MW
Positive Control
293T , mouse brain , PC-12
Predict Reactivity
Zebrafish, Bovine, Pig, Xenopus laevis, Rhesus Monkey(>80% identity)
PROPERTIES
Form
Liquid
Buffer
0.1M Tris-Glycine (pH7), 10% Glycerol
Preservative
0.01% Thimerosal
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
0.96 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Recombinant protein encompassing a sequence within the center region of human CTDSP2. The exact sequence is proprietary.
Purification
Purified by antigen-affinity chromatography.
Conjugation
Unconjugated
RRID
AB_1950056
Note
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET
Synonyms
CTD small phosphatase 2 , OS4 , PSR2 , SCP2
Cellular Localization
Nucleus
Background
Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. May contribute to the development of sarcomas.
Database
Research Area
DATA IMAGES
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GTX104889 WB Image
Sample (30 ug of whole cell lysate) A: 293T 12% SDS PAGE CTDSP2 antibody GTX104889 diluted at 1:1000
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GTX104889 WB Image
Sample (50 ug of whole cell lysate) A: Mouse brain 12% SDS PAGE GTX104889 diluted at 1:1000
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GTX104889 WB Image
CTDSP2 antibody detects CTDSP2 protein by Western blot analysis. A. 30 μg PC-12 whole cell lysate/extract 12 % SDS-PAGE CTDSP2 antibody (GTX104889) dilution: 1:1000
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REFERENCE
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REVIEW
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