GeneTex
  • Country / Location Selection

United States (US)

CTLA4 antibody [8F16]

Anti-CTLA4 antibody [8F16] used in Western Blot (WB). GTX52659

Cat No. GTX52659

Host

Mouse

Clonality

Monoclonal

Clone Name

8F16

Isotype

IgG2

Application

WB

Reactivity

Human
Package
100 μg ($379)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:1000
Not tested in other applications.

Calculated MW

25 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

500 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human recombinant CTLA-4

Purification

Protein G purified
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

ALPS5 , CD , CD152 , CELIAC3 , CTLA4 , GRD4 , GSE , IDDM12 , cytotoxic Tlymphocyte associated protein 4 , cytotoxic T-lymphocyte associated protein 4

Cellular Localization

Cell membrane

Background

This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-CTLA4 antibody [8F16] used in Western Blot (WB). GTX52659

GTX52659 WB Image

WB analysis of HEK293 overexpressing human CTLA-4 using GTX52659 CTLA4 antibody [8F16].

REFERENCE

There are currently no references for CTLA4 antibody [8F16] (GTX52659). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for CTLA4 antibody [8F16] (GTX52659). Be the first to share your experience with this product.
SDS
PBS.pdf
Package List Price ($)
$ 379