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CTLA4 antibody [BNI3] (PE)

Cat No. GTX00492-08

Host

Mouse

Clonality

Monoclonal

Clone Name

BNI3

Isotype

IgG2a

Application

FACS

Reactivity

Human
Package
100 test ($329)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
FACS 10 μl reagent / 100 μl of whole blood or 10⁶ cells in a suspension
Not tested in other applications.

Calculated MW

25 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 15mM sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE. Protect from light.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human CD152-IgG heavy chain fusion protein

Purification

Purified by size-exclusion chromatography

Conjugation

Phycoerythrin (PE)

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

ALPS5,CD,CD152,CELIAC3,CTLA4,GRD4,GSE,IDDM12,cytotoxic Tlymphocyte associated protein 4,cytotoxic T-lymphocyte associated protein 4

Cellular Localization

Cell membrane

Background

This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. [provided by RefSeq, Jul 2008]

Database

Research Area

REFERENCE

There are currently no references for CTLA4 antibody [BNI3] (PE) (GTX00492-08). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for CTLA4 antibody [BNI3] (PE) (GTX00492-08). Be the first to share your experience with this product.