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CTLA4 antibody [IHC004]

Anti-CTLA4 antibody [IHC004] used in IHC (Paraffin sections) (IHC-P). GTX57204

Cat No. GTX57204

Host Mouse
Clonality Monoclonal
Clone Name IHC004
Isotype IgG1
Application IHC-P
Reactivity Human
Package
500 μl ($439)
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-P 1:100-1:200
Not tested in other applications.

Calculated MW

25 kDa. ( Note )

Positive Control

Tonsil, Lymph Node, Colon, Thymus
PROPERTIES

Form

Liquid

Buffer

Tris buffer pH 7.3 - 7.7, 1% BSA, <0.1% Sodium Azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Antigen Species

Human

Immunogen

Recombinant CTLA4 protein.

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Cytotoxic T-Lymphocyte Associated Protein 4,Alps5,Cd,Cd152,Celiac3,Ctla-4,Grd4,Gse,Iddm12,Ctla4

Background

This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. [provided by RefSeq, Jul 2008]

Research Area

DATA IMAGES
Anti-CTLA4 antibody [IHC004] used in IHC (Paraffin sections) (IHC-P). GTX57204

GTX57204 IHC-P Image

IHC-P analysis of human tonsil tissue using GTX57204 CTLA4 antibody [IHC004]

REFERENCE
There are currently no references for CTLA4 antibody [IHC004] (GTX57204). Be the first to share your publications with this product.
REVIEW
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