*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
Tonsil, Lymph Node, Colon, Thymus
Tris buffer pH 7.3 - 7.7, 1% BSA, <0.1% Sodium Azide
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
Recombinant CTLA4 protein.
Protein A purified
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Cytotoxic T-Lymphocyte Associated Protein 4,Alps5,Cd,Cd152,Celiac3,Ctla-4,Grd4,Gse,Iddm12,Ctla4
This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. [provided by RefSeq, Jul 2008]