*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
Tonsil, Lymph Node, Colon, Thymus
Tris buffer pH 7.3 - 7.7, 1% BSA, <0.1% Sodium Azide
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
Batch dependent (Please refer to the vial label for the specific concentration.)
Recombinant CTLA4 protein.
Protein A purified
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Cytotoxic T-Lymphocyte Associated Protein 4 , Alps5 , Cd , Cd152 , Celiac3 , Ctla-4 , Grd4 , Gse , Iddm12 , Ctla4
This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. [provided by RefSeq, Jul 2008]