GeneTex

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United States (US)

CTLA4 antibody

Cat. No. GTX13486

Host

 Goat

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ELISA

Reactivity

 Mouse
Package
50 μg ($399)
See all CTLA4 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 0.1-0.2 μg/ml
ELISA 0.1-0.4 μg/ml
Not tested in other applications.

Calculated MW

25 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 5% Trehalose

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Mouse

Immunogen

purified recombinant mouse cytotoxic T-lymphocyte-associated molecule 4 extracellualr domain, expressed in mouse NSO cells.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

cytotoxic T-lymphocyte-associated protein 4 , Cd152 , Ctla-4 , Ly-56

Cellular Localization

Cell membrane

Background

CTLA4 has a critical role in T cell differentiation and contributes to the maintenance of peripheral T cell tolerance to self antigens. It exerts its major effects on T cell immune responses via regulation of the cell cycle and may be involved in T-cell activation. It binds to B7-1 (CD80) and B7-2 (CD86), and it contains 1 immunoglobulin-like V-type domain. Widely expressed with highest levels in lymphoid tissues.

Database

Research Area

REFERENCE

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REVIEW

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SDS
PBS.pdf
Package List Price ($)
$ 399