GeneTex
United States (US)

CUGBP1 antibody [3B1]

GTX29549_172_ICC-IF_18121410_398.jpg
GTX29549_1318_WB_18121410_667.jpg
GTX29549_1319_WB_18121410_503.jpg
GTX29549_93_FACS_18121410_393.jpg

Cat No. GTX29549

Host Mouse
Clonality Monoclonal
Clone Name 3B1
Isotype IgG1
Application WB, ICC/IF, IHC-P, IHC-Fr, FACS, IP, GSA
Reactivity Human, Mouse, Rat, Rabbit, Bovine, Pig, Primate
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500
ICC/IF 1:50 - 1:200
IHC-P 1:100 - 1:500
IHC-Fr 1:100 - 1:500
FACS 1 μg / 10⁶ cells
IP Assay dependent
GSA Assay dependent
Not tested in other applications.

Calculated MW

52 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

Tris-Glycine, 0.15M NaCl, 0.02% Sodium Azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Full-length human CUGBP1 [UniProt# Q92879]

Purification

Protein G purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Cugbp Elav-Like Family Member 1,Brunol2,Cug-Bp,Cugbp,Cugbp1,Eden-Bp,Nab50,Napor,Hnab50,Celf1

Cellular Localization

Nucleus,Cytoplasm

Background

Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. This gene may play a role in myotonic dystrophy type 1 (DM1) via interactions with the dystrophia myotonica-protein kinase (DMPK) gene. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq]

Database

Research Area

DATA IMAGES
GTX29549_172_ICC-IF_18121410_398.jpg

GTX29549 ICC/IF Image

ICC/IF analysis of normal and DM1 (dystrophia myotonica) myoblasts using GTX29549 CUGBP1 antibody [3B1].

GTX29549_1318_WB_18121410_667.jpg

GTX29549 WB Image

WB analysis of HeLa cell lysate using GTX29549 CUGBP1 antibody [3B1].

GTX29549_1319_WB_18121410_503.jpg

GTX29549 WB Image

WB analysis of multiple cell lysate using GTX29549 CUGBP1 antibody [3B1].

GTX29549_93_FACS_18121410_393.jpg

GTX29549 FACS Image

FACS (Intracellular staining) analysis of MCF-7 cells using GTX29549 CUGBP1 antibody [3B1].
Blue : Primary antibody
Orange : isotype control
Dilution : 1 μg/10⁶ cells

Package List Price ($)
$ 329