GeneTex
United States (US)

CX3CL1 antibody [4C5]

GTX15786_1537_WB_19011519_322.jpg
GTX15786_68_ELISA_19011519_659.jpg

Cat No. GTX15786

Host Mouse
Clonality Monoclonal
Clone Name 4C5
Isotype IgG
Application WB, ELISA
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:1000
ELISA Assay dependent
Not tested in other applications.

Calculated MW

42 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS, 1mg/ml BSA, 50% glycerol, 0.05% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Non-glycosylated, polypeptide chain containing 76 amino acids of chemokine domain expressed in E. coli.

Purification

Protein G purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

C-X3-C Motif Chemokine Ligand 1,Abcd-3,C3Xkine,Cxc3,Cxc3C,Ntn,Ntt,Scyd1,Fractalkine,Neurotactin,Cx3Cl1

Cellular Localization

Cell membrane,Secreted

Background

This gene belongs to the CX3C subgroup of chemokines, characterized by the number of amino acids located between the conserved cysteine residues. This is the only member of the CX3C subgroup, which contains three amino acids between cysteine residues, resulting in a Cys-X-X-X-Cys configuration. The encoded protein contains an extended mucin-like stalk with a chemokine domain on top, and exists in both a membrane-anchored form where it acts as a binding molecule, or, in soluble form, as a chemotactic cytokine. The mature form of this protein can be cleaved at the cell surface, yielding different soluble forms that can interact with the G-protein coupled receptor, C-X3-C motif chemokine receptor 1 gene product. This gene plays a role in a wide range of diseases, including cancer, vasculitis, neuropathies, atherosclerosis, inflammatory diseases, and in human immunodeficiency virus infections. [provided by RefSeq, Sep 2017]

Database

Research Area

DATA IMAGES
GTX15786_1537_WB_19011519_322.jpg

GTX15786 WB Image

WB analysis of 0.25µg of recombinant human Fractalkine using GTX15786 CX3CL1 antibody [4C5].
Dilution : 1:1000

GTX15786_68_ELISA_19011519_659.jpg

GTX15786 ELISA Image

ELISA analysis of 1 µg/ml recombinant human Fractalkine (CX3CL1)protein buffer using serial diluted GTX15786 CX3CL1 antibody [4C5].