GeneTex
United States (US)

CX3CL1 antibody

CX3CL1-antibody_WB_GTX29819-1_18121409_473.jpg

Cat No. GTX29819

Host Rabbit
Clonality Polyclonal
Application WB
Reactivity Human
APPLICATION

Application Note

For WB: Use at a dilution of 1:1,500 - 1:2,500. Optimal dilutions/concentrations should be determined by the researcher.

Calculated MW

42 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

Phosphate buffered saline, pH 7.2, containing 0.1% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1mg/ml(Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fragment - amino acids 379-397 of human CX3CL1 (fractalkine)

Purification

Protein A affinity purified
From polyclonal serum

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

ABCD-3, C3Xkine, CXC3, CXC3C, NTN, NTT, SCYD1, fractalkine, neurotactin, ABCD 3, ABCD3

Background

CX3CL1, also known as fractalkine and neurotactin, is a membrane bound CX3C chemokine. The mature protein is part of a 397 amino acid precursor and consists of a chemokine domain of 76 amino acids, a mucin stalk of 241 amino acids, a putative transmembrane domain of 18 amino acids, and an intracellular tail of 37 amino acids. Within the chemokine domain the first two cysteine residues are separated by 3 amino acids (CX3C). CX3CL1 message is found in high abundance in the brain, kidney, lung and heart tissues. CX3CL1 is chemotactic for monocytes and other leukocytes including NK cells, lymphocytes, and may play a role in brain inflammation.

Database

Research Area

DATA IMAGES
CX3CL1-antibody_WB_GTX29819-1_18121409_473.jpg

GTX29819 WB Image

Western blot detection of Fractalkine protein in brain tissue