GeneTex
United States (US)

CX3CR1 antibody

GTX31648_2828_WB_20180221_18121410_122.jpg
GTX31648_247_ICC-IF_20180221_18121410_837.jpg
GTX31648_1313_IHC-P_20180221_18121410_519.jpg

Cat No. GTX31648

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF, IHC-P, ELISA
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 0.5 μg/mL
ICC/IF Assay dependent
IHC-P 10 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

40 kDa. ( Note )

Positive Control

THP-1 Cell Slide(GTX25540) , THP-1 Cell Lysate(GTX27913) , 3T3 Cell Lysate
PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

CX3CR1 antibody was raised against a peptide corresponding to amino acids in a extracellular loop of human CX3CR1.The immunogen is located within amino acids 160 - 210 of CX3CR1.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

C-X3-C Motif Chemokine Receptor 1,Ccrl1,Cmkbrl1,Cmkdr1,Gpr13,Gprv28,V28,Cx3Cr1

Background

Fractalkine is a transmembrane protein and chemokine involved in the adhesion and migration of leukocytes. The protein encoded by this gene is a receptor for fractalkine. The encoded protein also is a coreceptor for HIV-1, and some variations in this gene lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS. Four transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]

Database

Research Area

DATA IMAGES
GTX31648_2828_WB_20180221_18121410_122.jpg

GTX31648 WB Image

WB analysis of THP-1 cell lysate in (A) the absence and (B) the presence of blocking peptide using GTX31648 CX3CR1 antibody.
Working concentration : 1 μg/ml

GTX31648_247_ICC-IF_20180221_18121410_837.jpg

GTX31648 ICC/IF Image

ICC/IF analysis of THP-1 cells using GTX31648 CX3CR1 antibody.
Working concentration : 20 μg/ml

GTX31648_1313_IHC-P_20180221_18121410_519.jpg

GTX31648 IHC-P Image

IHC-P analysis of human spleen tissue using GTX31648 CX3CR1 antibody.
Working concentration : 10 μg/ml

Package List Price ($)
$ 329