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CX3CR1 peptide

Cat. No. GTX28125

Reference 1

Application

 Neutralizing/Inhibition

Species

 Human
Package
50 μg ($139)
See all CX3CR1 products

APPLICATION

Application Note

The peptide is used for blocking the activity of anti-CX3CR1 (GTX28021).Incubating the peptide with equal volume of antibody for 30 min at 37ºC usually completely blocksthe antibody activity in Western blotting.

PROPERTIES

Form

Liquid

Buffer

PBS pH7.2, 10mM NaH₂PO₄, 10mM Na₂HPO₄, 130mM NaCl, 0.1% BSA

Preservative

0.02% Sodium azide

Storage

Store the peptide at -20ºC, stable for one year.

Concentration

0.20 mg/ml (Please refer to the vial label for the specific concentration.)

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

C-X3-C Motif Chemokine Receptor 1 , Ccrl1 , Cmkbrl1 , Cmkdr1 , Gpr13 , Gprv28 , V28 , Cx3Cr1

Background

CX3CR1 is one of the chemokine receptors that are required as co-receptors for HIV infection. The genes encoding human, mouse, and rat CX3CR1 were cloned and designated V28 and CMKBRL1, CX3CR1, and RBS11, respectively. The encoded seven transmembrane protein was recently identified as the receptor for a novel transmembrane molecule, fractalkine, and renamed CX3CR1. Recently, CX3CR1 was found to serve as a co-receptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by fractokine. CX3CR1 mediates leukocyte migration and adhesion. CX3CR1 is expressed in a variety of human tissues and cell lines.

Research Area

REFERENCE

Application Reference

Zhou JJ et al. PLoS One 2018; 13 (4) : e0195657 DEC205-DC targeted DNA vaccine against CX3CR1 protects against atherogenesis in mice.
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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 139