CXCL1 / GRO alpha antibody [N3C3]

Name: CXCL1 / GRO alpha antibody [N3C3]
Brand: GeneTex
SKU: GTX108435
Price: 399.00 USD
Rating: 5 (1 reviews)

Anti-CXCL1 / GRO alpha antibody [N3C3] used in Western Blot (WB). GTX108435

Cat. No. GTX108435

Reference 2

Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Application	WB
Reactivity	Human
Package	100 μl ($399), 25 μl ($169)

See all CXCL1 / GRO alpha products

View product citations for antibody GTX108435 on CiteAb

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Recommended Dilution
WB	1:500-1:3000

Not tested in other applications.

Calculated MW

11 kDa. ( Note )

Positive Control

CXCL1 transfected 293T cell

Predict Reactivity

Rhesus Monkey(>80% identity)

PROPERTIES

Form

Liquid

Buffer

0.1M Tris, 0.1M Glycine, 10% Glycerol

Preservative

0.01% Thimerosal

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human CXCL1 / GRO alpha. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_1950074

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

C-X-C motif chemokine ligand 1 , FSP , GRO1 , GROa , MGSA , MGSA-a , NAP-3 , SCYB1

Cellular Localization

Secreted

Background

Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues; the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. CXC chemokines are further subdivided into ELR and non-ELR types based on the presence or absence of a glu-leu-arg sequence adjacent and N terminal to the CXC motif. ELR types are chemotactic for neutrophils, while non-ELR types are chemotactic for lymphocytes.[supplied by OMIM]

Database

Gene ID: 2919 CXCL1
UniProt: P09341 CXCL1

Research Area

DATA IMAGES

GTX108435 WB Image

Western Blot analysis of CXCL1 expression in transfected 293T cell line by CXCL1 polyclonal antibody.
A: Non-transfected lysate.
B: CXCL1 transfected lysate.
15% SDS PAGE
GTX108435 diluted at 1:500

REFERENCE

Application Reference

Chao CC et al. Cancers (Basel) 2020; 12 (2) CXCL1/CXCR2 Paracrine Axis Contributes to Lung Metastasis in Osteosarcoma.

Application : WB

Reactivity : Human

Yuan Y et al. J Cell Mol Med 2019; (Epub) BAG3-positive pancreatic stellate cells promote migration and invasion of pancreatic ductal adenocarcinoma.

Application : WB

Reactivity : Human

Submit a Reference

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