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CXCL14 antibody [N3C3]

KO/KD Overexpression
Anti-CXCL14 antibody [N3C3] used in IHC (Paraffin sections) (IHC-P). GTX108431
Anti-CXCL14 antibody [N3C3] used in Western Blot (WB). GTX108431
Anti-CXCL14 antibody [N3C3] used in IHC (Paraffin sections) (IHC-P). GTX108431

Cat. No. GTX108431

Reference 3

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P

Reactivity

 Human, Mouse
Package
100 μl ($399),
25 μl ($169)
See all CXCL14 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:3000
ICC/IF Assay dependent
IHC-P 1:100-1:1000
Not tested in other applications.

Calculated MW

13 kDa. ( Note )

Product Note

Knockdown/Knockout validation was supported by references (PMID:37056937)

Predict Reactivity

Rat, Bovine, Pig, Rhesus Monkey(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS, 20% Glycerol

Preservative

0.025% ProClin 300

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1.44 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human CXCL14. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_1950075

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

C-X-C motif chemokine ligand 14 , BMAC , BRAK , KEC , KS1 , MIP-2g , MIP2G , NJAC , SCYB14

Cellular Localization

Secreted

Background

This gene belongs to the cytokine gene family which encode secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC (Cys-X-Cys) subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes but not for lymphocytes, dendritic cells, neutrophils or macrophages. It has been implicated that this cytokine is involved in the homeostasis of monocyte-derived macrophages rather than in inflammation. [provided by RefSeq]

Database

Research Area

DATA IMAGES

Anti-CXCL14 antibody [N3C3] used in IHC (Paraffin sections) (IHC-P). GTX108431

GTX108431 IHC-P Image

Immunohistochemical analysis of paraffin-embedded human renal cell carcinoma , using CXCL14(GTX108431) antibody at 1:100 dilution.
Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min

Anti-CXCL14 antibody [N3C3] used in Western Blot (WB). GTX108431

GTX108431 WB Image

Human tissue extract (30 μg) was separated by 15% SDS-PAGE, and the membrane was blotted with CXCL14 antibody [N3C3] (GTX108431) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-CXCL14 antibody [N3C3] used in IHC (Paraffin sections) (IHC-P). GTX108431

GTX108431 IHC-P Image

Immunohistochemical analysis of paraffin-embedded human renal cell carcinoma , using CXCL14(GTX108431) antibody at 1:100 dilution.
Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min

REFERENCE

Application Reference

A Goto et al. Commun Biol 2023; 6 (1) : 1173 C-X-C domain ligand 14-mediated stromal cell–macrophage interaction as a therapeutic target for hand dermal fibrosis
Application : WB, ICC/IF, IHC-P
Reactivity : Human, Mouse
Chang TM et al. Int J Biol Sci 2023; 19 (5) : 1455-1470 CXCL14 promotes metastasis of non-small cell lung cancer through ACKR2-depended signaling pathway.
Application : WB, IHC-P
Reactivity : Human
Cao Q et al. Biochem Biophys Res Commun 2013; 435 (4) : 664-70 Genetic deletion of Cxcl14 in mice alters uterine NK cells.
Application : IHC-P
Reactivity : Mouse
Submit a Reference

REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 399
$ 169