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CXCL8 / IL8 antibody [6217]

Cat. No. GTX10768

Reference 1

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 6217

Isotype

 IgG1

Application

 WB, ICC/IF, FACS, ELISA, Neutralizing/Inhibition

Reactivity

 Human
Package
100 μg ($399)
See all CXCL8 / IL8 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1-2 μg/ml
ICC/IF 25 μg/ml
FACS 25 μg/ml (10 μl/1-5 X 10⁵ cells)
ELISA 0.5 μg/ml
Neutralizing/Inhibition 0.08-0.4 μg/ml
Not tested in other applications.

Calculated MW

11 kDa. ( Note )

Positive Control

calcium ionophore- and PMA-stimulated human peripheral blood mononuclear cells

PROPERTIES

Form

Liquid

Buffer

PBS carbohydrates

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

purified, E. coli-derived, recombinant human IL-8.

Purification

Purified immunoglobulin

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

C-X-C motif chemokine ligand 8 , GCP-1 , GCP1 , IL8 , LECT , LUCT , LYNAP , MDNCF , MONAP , NAF , NAP-1 , NAP1

Cellular Localization

Secreted

Background

IL8, formerly called monocyte derived neutrophil chemotactic factor, belongs to the chemokine alpha family. Human endothelial IL8 is an 8.9 kDa protein containing 77 amino acid residues. IL8 exhibits chemotactic activity in vitro for T cells, basophils and neutrophils and promotes degranulation.

Database

Research Area

REFERENCE

Application Reference

Wang J et al. Int J Mol Sci 2022; 23 (21) ENO1 Binds to ApoC3 and Impairs the Proliferation of T Cells via IL-8/STAT3 Pathway in OSCC.
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REVIEW

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SDS
PBS.pdf
Package List Price ($)
$ 399