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CXCR1 antibody [C2C3], C-term

Anti-CXCR1 antibody [C2C3], C-term used in IHC (Paraffin sections) (IHC-P). GTX100389
Anti-CXCR1 antibody [C2C3], C-term used in IHC (Paraffin sections) (IHC-P). GTX100389
Anti-CXCR1 antibody [C2C3], C-term used in IHC (Paraffin sections) (IHC-P). GTX100389

Cat. No. GTX100389

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

ICC/IF, IHC-P, IHC-Fr

Reactivity

Human, Mouse
Package
100 μl ($399),
25 μl ($169)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
ICC/IF 1:100-1:1000
IHC-P 1:100-1:1000
IHC-Fr Assay dependent
Not tested in other applications.

Calculated MW

40 kDa. ( Note )

Predict Reactivity

Chimpanzee(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS, 20% Glycerol

Preservative

0.025% ProClin 300

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1.97 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide encompassing a sequence within the Intracellular domain of human CXCR1. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_1240576

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

C-X-C motif chemokine receptor 1 , C-C , C-C-CKR-1 , CD128 , CD181 , CDw128a , CKR-1 , CMKAR1 , IL8R1 , IL8RA , IL8RBA

Cellular Localization

Cell membrane

Background

The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. [provided by RefSeq]

Database

Research Area

DATA IMAGES

Anti-CXCR1 antibody [C2C3], C-term used in IHC (Paraffin sections) (IHC-P). GTX100389

GTX100389 IHC-P Image

CXCR1 antibody [C2C3], C-term detects CXCR1 protein at cell membrane by immunohistochemical analysis.
Sample: Paraffin-embedded human esophageal carcinoma.
CXCR1 stained by CXCR1 antibody [C2C3], C-term (GTX100389) diluted at 1:500.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

Anti-CXCR1 antibody [C2C3], C-term used in IHC (Paraffin sections) (IHC-P). GTX100389

GTX100389 IHC-P Image

CXCR1 antibody [C2C3], C-term detects IL8RA protein at cytosol on human hepatoma by immunohistochemical analysis.
Sample: Paraffin-embedded hepatoma.
CXCR1 antibody [C2C3], C-term (GTX100389) dilution: 1:500.

Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min

Anti-CXCR1 antibody [C2C3], C-term used in IHC (Paraffin sections) (IHC-P). GTX100389

GTX100389 IHC-P Image

CXCR1 antibody [C2C3], C-term detects CXCR1 protein at cell membrane by immunohistochemical analysis.
Sample: Paraffin-embedded human breast carcinoma.
CXCR1 stained by CXCR1 antibody [C2C3], C-term (GTX100389) diluted at 1:500.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

REFERENCE

REVIEW

CXCR1 antibody [C2C3], C-term Cat. No. GTX100389

Rating ( Average 5 based on 5 users reviews)
Application
Immunocytochemistry/ Immunofluorescence(ICC/IF) ( Average 5 based on 1 users reviews)
IHC (Paraffin sections)(IHC-P) ( Average 5 based on 3 users reviews)
IHC (Frozen sections)(IHC-Fr) ( Average 5 based on 1 users reviews)
Date : Anonymous submitted on 10-Aug-2021
Score :
Application Tested : IHC-P
Sample Species : Ms
Figure Note : The data was peer reviewed and published in the journal Nat Commun in 2016.PMID: 27241286
Date : Anonymous submitted on 10-Aug-2021
Score :
Application Tested : IHC-P
Sample Species : Ms
Figure Note : The data was peer reviewed and published in the journal Nat Commun in 2016.PMID: 27241286
Date : Anonymous submitted on 10-Aug-2021
Score :
Application Tested : IHC-P
Sample Species : Ms
Figure Note : The data was peer reviewed and published in the journal Nat Commun in 2016.PMID: 27241286
Date : Anonymous submitted on 18-Mar-2021
Score :
Application Tested : IHC-Fr
Sample Species : Hu
Figure Note : The data was peer reviewed and published in the journal BMC Cancer in 2014. PMID: 25123545
Date : Anonymous submitted on 15-Feb-2019
Score :
Application Tested : ICC/IF
Sample Species : Ms
Sample : CT26 cells
Blocking : 2% FBS in PBS, 25°C, 0.15Hr
Fixation : 4% paraformaldehyde
Primary Antibody : 1:100, 4°C, 16Hr
SDS
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 399
$ 169