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CXCR1 antibody [HL2674]

Recombinant antibody Orthogonal
Anti-CXCR1 antibody [HL2674] used in IHC (Paraffin sections) (IHC-P). GTX639338
Anti-CXCR1 antibody [HL2674] used in IHC (Paraffin sections) (IHC-P). GTX639338
Anti-CXCR1 antibody [HL2674] used in Western Blot (WB). GTX639338

Cat. No. GTX639338

Host

 Rabbit

Clonality

 Monoclonal

Clone Name

 HL2674

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399),
25 μl ($169)
See all CXCR1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:3000
IHC-P Assay dependent
Not tested in other applications.

Calculated MW

40 kDa. ( Note )

Product Note

This antibody was raised against human CXCR1 Extracellular domain.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide encompassing a sequence within the Extracellular domain of human CXCR1. The exact sequence is proprietary.

Purification

Affinity purified by Protein A.

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

C-X-C motif chemokine receptor 1 , C-C , C-C-CKR-1 , CD128 , CD181 , CDw128a , CKR-1 , CMKAR1 , IL8R1 , IL8RA , IL8RBA

Cellular Localization

Cell membrane; Multi-pass membrane protein

Background

The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-CXCR1 antibody [HL2674] used in IHC (Paraffin sections) (IHC-P). GTX639338

GTX639338 IHC-P Image

CXCR1 antibody [HL2674] detects CXCR1 protein at cell membrane by immunohistochemical analysis.
Sample: Paraffin-embedded mouse liver.
CXCR1 stained by CXCR1 antibody [HL2674] (GTX639338) diluted at 1:100.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

Anti-CXCR1 antibody [HL2674] used in IHC (Paraffin sections) (IHC-P). GTX639338

GTX639338 IHC-P Image

CXCR1 antibody [HL2674] detects CXCR1 protein at cell membrane by immunohistochemical analysis.
Sample: Paraffin-embedded rat liver.
CXCR1 stained by CXCR1 antibody [HL2674] (GTX639338) diluted at 1:100.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

Anti-CXCR1 antibody [HL2674] used in Western Blot (WB). GTX639338

GTX639338 WB Image

Orthogonal

Boiled and unboiled, non-transfected (–) and transfected (+) 293T whole cell extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with CXCR1 antibody [HL2674] (GTX639338) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

REFERENCE

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REVIEW

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Package List Price ($)
$ 399
$ 169
Custom Conjugations