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CXCR3 antibody [7K22]

Cat No. GTX52676

Host

Mouse

Clonality

Monoclonal

Clone Name

7K22

Isotype

IgG1

Application

IHC-Fr, FACS, Neutralizing/Inhibition

Reactivity

Human
Package
100 μg ($329)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-Fr 1:20 - 1:100
FACS 1:50 - 1:200
Neutralizing/Inhibition Assay dependent
Not tested in other applications.

Calculated MW

41 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

500 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human recombinant CXCR3

Purification

Protein G purified
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

CD182 , CD183 , CKRL2 , CMKAR3 , CXC motif chemokine receptor 3 , CXCR3 , GPR9 , IP10R , MigR , C-X-C motif chemokine receptor 3

Cellular Localization

Cell membrane

Background

This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4 (PMID:12782716). [provided by RefSeq, Jun 2011]

Database

Research Area

REFERENCE

There are currently no references for CXCR3 antibody [7K22] (GTX52676). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for CXCR3 antibody [7K22] (GTX52676). Be the first to share your experience with this product.
SDS
PBS.pdf
Package List Price ($)
$ 329