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CXCR3 antibody [CXCR3-173]

Cat. No. GTX14657

Host

 Armenian Hamster

Clonality

 Monoclonal

Clone Name

 CXCR3-173

Isotype

 IgG

Application

 FACS, Neutralizing/Inhibition

Reactivity

 Mouse
Package
250 μg ($399)
See all CXCR3 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
FACS Assay dependent
Neutralizing/Inhibition Assay dependent

Note :

Neutralizing/Inhibition
The binding of CXCR3-173 to CXCR3 is reported to inhibit receptor binding of CXCL10 and CXCL11 but not CXCL9.
Not tested in other applications.

Calculated MW

41 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Filter-sterilized PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Mouse

Immunogen

Peptide consisting of amino acids 1-37 of mouse CXCR3

Purification

Protein G purified
From tissue culture supernatant

Purity

>95% (Determined by SDS-PAGE)

Endotoxin

< 0.002 EU/弮g (Determined by LAL assay)

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Cellular Localization

Cell membrane

Background

This gene encodes a transmembrane protein that functions as a receptor for C-X-R chemokines. Signalling through this protein regulates a variety of biological processes, including inflammation, immunity, and would healing. This protein also plays a role in tumor growth and metastasis. [provided by RefSeq, May 2015]

Database

Research Area

REFERENCE

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REVIEW

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Package List Price ($)
$ 399